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Coffee's Secret to Long Life! ☕
Daily news that is actually intellectually stimulating.

PhD Level: Daily Curated Tech News for Entrepreneurs, by EntrepreneursDear reader,
I’m a big coffee drinker (at least 2 cups a day) and now we have one more reason (anti-aging? sure!) to be a coffee addict!
Let’s get into it →
Scientists Reveal Caffeine Activates Ancient Longevity Switch

A team at Queen Mary University of London discovered that caffeine doesn’t just wake you up—it activates AMPK, a fundamental cellular energy sensor conserved across hundreds of millions of years. By turning on AMPK in yeast cells, caffeine mimics a key pathway for coping with stress and extending lifespan.
My take: So it is such a well-studied molecule, AMPK. This study reminds me of some studies before showing caffeine consumption and cardiovascular diseases, and caffeine’s effect on AMPK-related pathways like TORC1 inhibition.
Takeaways
Why It Matters
Health & longevity boost: Activating AMPK may underpin coffee’s links to improved health and longer life.
Beyond caffeine: AMPK is also targeted by drugs like metformin, spotlighting future anti-aging therapies.
Evolutionary insight: The finding shows an ancient stress-response mechanism shared from yeast to humans.
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Stay curious,
The PhD Level Team
☕️🐻 Powered by caffeine & curiosity